Article
Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling
2023-11-03
Abstract excerpt
Immunoglobulins (Ig), which exist either as B-cell receptors (BCR) on the surface of B cells or as antibodies when secreted, play a key role in the recognition and response to antigenic threats. The capability to jointly characterize the BCR and antibody repertoire is crucial in understanding human adaptive immunity. From peripheral blood, bulk BCR sequencing (bulkBCR-seq) currently provides the highest sampling d...
Topics
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- Cytomegalovirus and herpesvirus research
- Glycosylation and Glycoproteins Research
- Immune Cell Function and Interaction
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- Systemic Lupus Erythematosus Research
- T-cell and B-cell Immunology
- vaccines and immunoinformatics approaches
Identifiers and source
- Literature Corpus work
- 10e84d6e-1030-592d-9bbd-9744a0a48a69
- DOI
- 10.1101/2023.11.01.565093