Article

Diffusible fraction of niche BMP ligand safeguards stem-cell differentiation

2022-09-15

Abstract excerpt

Drosophila male germline stem cells (GSCs) reside at the tip of the testis and surround a cluster of niche cells. It has been believed that the niche-derived Decapentaplegic (Dpp) has a role in maintaining stem cells in close proximity but has no role in the differentiating cells spaced one-cell layer away. However, the range of Dpp diffusion has never been tested. Here, using genetically encoded nanobodies called...

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Literature Corpus work: 7dd9e779-e72c-5e86-99ef-2636e8687163
DOI: 10.1101/2022.09.13.507868

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