Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distant activation of Notch signaling induces stem cell niche assembly.

PLoS genetics - 1 Mar 2021

Yatsenko Andriy S, Shcherbata Halyna R

Abstract excerpt

Here we show that multiple modes of Notch signaling activation specify the complexity of spatial cellular interactions necessary for stem cell niche assembly. In particular, we studied the formation of the germline stem cell niche in Drosophila ovaries, which is a two-step process whereby terminal filaments are formed first. Then, terminal filaments signal to the adjacent cap cell precursors, resulting in Notch...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Drosophila
Share to Germ Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Organogenesis

Share to Receptors, Notch

Share to Stem Cell Niche

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 33780456
DOI: 10.1371/journal.pgen.1009489
PMCID: PMC8031783

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distant activation of Notch signaling induces stem cell niche assembly.PMID 33780456Read ↗

Lmx1a is required for the development of the ovarian stem cell niche in Drosophila.Semantic proximity Read ↗

<i>Drosophila</i> ovarian germline stem cell cytocensor projections dynamically receive and attenuate BMP signalingSemantic proximity Read ↗

An epithelial niche in the Drosophila ovary undergoes long-range stem cell replacement.Semantic proximity Read ↗

Alternative direct stem cell derivatives defined by stem cell location and graded Wnt signalling.Semantic proximity Read ↗

A DTC Niche Plexus Surrounds the Germline Stem Cell Pool in Caenorhabditis elegansSemantic proximity Read ↗

The Drosophila female germline stem cell lineage acts to spatially restrict DPP function within the niche.Semantic proximity Read ↗

Drosophila's contribution to stem cell researchSemantic proximity Read ↗

CSN maintains the germline cellular microenvironment and controls the level of stem cell genes via distinct CRLs in testes of Drosophila melanogaster.Semantic proximity Read ↗

Wingless signaling regulates the maintenance of ovarian somatic stem cells in Drosophila.Semantic proximity Read ↗

An actomyosin network organizes niche morphology and responds to feedback from recruited stem cellsSemantic proximity Read ↗

Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue.Semantic proximity Read ↗

Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.