Article
The Drosophila female germline stem cell lineage acts to spatially restrict DPP function within the niche.
Science signaling - 27 Jul 2010
Liu Ming, Lim Tit Meng, Cai Yu
Abstract excerpt
Maintenance of stem cells requires spatially restricted, niche-associated signals. In the Drosophila female germline stem cell (GSC) niche, Decapentaplegic (DPP) is the primary niche-associated factor and functions over a short range to promote GSC self-renewal rather than differentiation. Here, we show that the GSC lineage and, more specifically, the stem cells themselves participate in the spatial restriction...
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