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Article

Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders.

eLife - 2 Nov 2020

Melamed David, Kalderon Daniel

Abstract excerpt

Many adult stem cell communities are maintained by population asymmetry, where stochastic behaviors of multiple individual cells collectively result in a balance between stem cell division and differentiation. We investigated how this is achieved for Drosophila Follicle Stem Cells (FSCs) by spatially-restricted niche signals. FSCs produce transit-amplifying Follicle Cells (FCs) from their posterior face and...

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Identifiers

PMID: 33135631
DOI: 10.7554/eLife.61204
PMCID: PMC7695452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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