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Diffusible fraction of niche BMP ligand safeguards stem-cell differentiation

7 Feb 2024

Abstract excerpt

Drosophila male germline stem cells (GSCs) reside at the tip of the testis and surround a cluster of niche cells. Decapentaplegic (Dpp) is one of the well-established ligands and has a major role in maintaining stem cells located in close proximity. However, the existence and the role of the diffusible fraction of Dpp outside of the niche have been unclear. Here, using genetically-encoded nanobodies called...

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PMID: 38326318
DOI: 10.1038/s41467-024-45408-7

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Diffusible fraction of niche BMP ligand safeguards stem-cell differentiationPMID 38326318Read ↗

Diffusible fraction of niche BMP ligand safeguards stem-cell differentiationSemantic proximity Read ↗

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