Article
decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary.
Cell - 24 Jul 1998
Xie T, Spradling A C
Abstract excerpt
Stem cells are thought to occupy special local environments, or niches, established by neighboring cells that give them the capability for self-renewal. Each ovariole in the Drosophila ovary contains two germline stem cells surrounded by a group of differentiated somatic cells that express hedgeh...
Topics
- Activin Receptors
- Animals
- Cell Differentiation
- Cell Division
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Female
- Germinoma
- Insect Proteins
- Mutation
- Ovary
- Protein Serine-Threonine Kinases
- Receptors, Cell Surface
- Receptors, Growth Factor
- Receptors, Transforming Growth Factor beta
- Repressor Proteins
- Signal Transduction