Article

Dissection of Major Depressive Disorder using polygenic risk scores for Schizophrenia in two independent cohort

2016-05-24

Abstract excerpt

Major depressive disorder (MDD) is known for its substantial clinical and suspected causal heterogeneity. It is characterised by low mood, psychomotor slowing, and increased levels of the personality trait neuroticism; factors which are also associated with schizophrenia (SCZ). It is possible that some cases of MDD may have a substantial genetic loading for SCZ. A sign of the presence of SCZ-like MDD sub-groups wo...

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Literature Corpus work: 7dbc3efc-b551-53a0-aff1-9388b46d98d7
DOI: 10.1101/054973

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