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Article

Phenotypically independent profiles relevant to mental health are genetically correlated.

Translational psychiatry - 1 Apr 2021

Roelfs Daniel, Alnæs Dag, Frei Oleksandr, van der Meer Dennis, Smeland Olav B, Andreassen Ole A, Westlye Lars T, Kaufmann Tobias

Abstract excerpt

Genome-wide association studies (GWAS) and family-based studies have revealed partly overlapping genetic architectures between various psychiatric disorders. Given clinical overlap between disorders, our knowledge of the genetic architectures underlying specific symptom profiles and risk factors is limited. Here, we aimed to derive distinct profiles relevant to mental health in healthy individuals and to study...

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Identifiers

PMID: 33795632
DOI: 10.1038/s41398-021-01313-x
PMCID: PMC8016894

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