Article

Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

2019-06-07

Abstract excerpt

<h4>Background</h4> Substantial clinical heterogeneity of major depressive disorder (MDD) suggests it may group together individuals with diverse aetiologies. Identifying distinct subtypes should lead to more effective diagnosis and treatment, while providing more useful targets for further research. Genetic and clinical overlap between MDD and schizophrenia (SCZ) suggests an MDD subtype may share underlying mech...

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Literature Corpus work: 1d33b2b5-aba3-50c2-94bf-3049597e59f2
DOI: 10.1101/663724

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