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Article

Enhancers in embryonic stem cells are enriched for transposable elements and genetic variations associated with cancers.

Nucleic acids research - 1 Sept 2011

Teng Li, Firpi Hiram A, Tan Kai

Abstract excerpt

Using an enhancer-associated epigenetic signature, we made genome-wide predictions of transcriptional enhancers in human B and T lymphocytes and embryonic stem cells (ES cells). We validated and characterized the predicted enhancers using four types of information, including overlap with other genomic marks for enhancers; association with cell-type-specific genes; enrichment of cell-type-specific transcription...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21685454
DOI: 10.1093/nar/gkr476
PMCID: PMC3177211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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