Article

Global mapping of the energetic and allosteric landscapes of protein binding domains

2021-09-14

Abstract excerpt

Allosteric communication between distant sites in proteins is central to nearly all biological regulation but still poorly characterised for most proteins, limiting conceptual understanding, biological engineering and allosteric drug development. Typically only a few allosteric sites are known in model proteins, but theoretical, evolutionary and some experimental studies suggest they may be much more widely distri...

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Literature Corpus work: 7cf73c58-8394-5236-8f7b-0e2e36fb3116
DOI: 10.1101/2021.09.14.460249

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