Article

Polygenic modulation of lipoprotein(a)-associated cardiovascular risk

2020-02-25

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Aims</h4> Elevated levels of lipoprotein(a) are one of the strongest inherited risk factors for coronary artery disease (CAD). However, there is variability in cardiovascular risk among individuals with elevated lipoprotein(a). The sources of this variability are incompletely understood. We assessed the effects of a genomic risk score (GRS) for CAD on risk of myocardial infarction among indiv...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7c92047d-05f1-5648-bc7b-d4b7af4640a0
DOI: 10.1101/2020.02.22.20026757

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Polygenic modulation of lipoprotein(a)-associated cardiovascular riskDOI 10.1101/2020.02.22.20026757Read

Clinical Utility of Lipoprotein(a) and <i>LPA</i> Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular DiseaseSemantic proximity Read

Polygenic Hyperlipidemias and Coronary Artery Disease RiskSemantic proximity Read

Polygenic Hyperlipidemias and Coronary Artery Disease Risk.Semantic proximity Read

Polygenic Risk Score Modifies Risk of Coronary Artery Disease Conferred by Low-Density Lipoprotein CholesterolSemantic proximity Read

Polygenic Risk for Coronary Artery Disease in the Scottish and English PopulationSemantic proximity Read

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary preventionSemantic proximity Read

Association of Genetically Predicted Levels of Circulating Blood Lipids with Coronary Artery Disease IncidenceSemantic proximity Read

Associations of Blood Lipid-Related Polygenic Scores, Lifestyle Factors and Their Combined Effects with Risk of Coronary Artery Disease in the UK Biobank Cohort.Semantic proximity Read

Polygenic risk for coronary artery disease in the Scottish and English population.Semantic proximity Read

The Inherited Basis of Coronary Artery Disease.Semantic proximity Read

Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry.Semantic proximity Read

Genetics and Pathophysiological Mechanisms of Lipoprotein(a)-Associated Cardiovascular Risk.Semantic proximity Read