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Article

The Inherited Basis of Coronary Artery Disease.

The New England journal of medicine - 5 Feb 2026

Schunkert Heribert, Natarajan Pradeep, Samani Nilesh J

Abstract excerpt

Investigations of the genetic basis of coronary artery disease have led to advances in mechanistic insights, therapeutics, prevention, and risk prediction. Indeed, most contemporary medicines for coronary artery disease target pathways that promote atherosclerosis due to underpinning genetic mechanisms. Monogenic causes of coronary artery disease occur in approximately 1 out of 250 people and mostly result in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41870454
DOI: 10.1056/NEJMra2405153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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