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Article

Polygenic risk for coronary artery disease in the Scottish and English population.

BMC cardiovascular disorders - 7 Dec 2021

Yang Chuhua, Starnecker Fabian, Pang Shichao, Chen Zhifen, Güldener Ulrich, Li Ling, Heinig Matthias, Schunkert Heribert

Abstract excerpt

BACKGROUND: Epidemiological studies have repeatedly observed a markedly higher risk for coronary artery disease (CAD) in Scotland as compared to England. Up to now, it is unclear whether environmental or genetic factors might explain this phenomenon. METHODS: Using UK Biobank (UKB) data, we assessed CAD risk, based on the Framingham risk score (FRS) and common genetic variants, to explore the respective...

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Identifiers

PMID: 34876023
DOI: 10.1186/s12872-021-02398-4
PMCID: PMC8650538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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