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Pro-inflammatory innate-like T cells are expanded in the blood and inflamed intestine in Crohn’s Disease

2022-05-14

Abstract excerpt

<h4>ABSTRACT</h4> A complex and tissue-specific network of cells including T lymphocytes maintains intestinal homeostasis. To address disease and tissue-specific alterations, we performed a T cell-centric mass cytometry analysis of peripheral and intestinal lymphocytes from patients with Crohn’s disease (CD) and healthy donor PBMCs. We compared inflamed and not inflamed tissue areas of bowel resections. Chronic in...

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Identifiers and source

Literature Corpus work
51e698a1-fe53-5d27-bbdd-f51f89dcacaa
DOI
10.1101/2022.05.12.22274864
Open publication

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