Article

Estimating Heritability and Genetic Correlation in Case Control Studies Directly and with Summary Statistics

2018-02-03

Abstract excerpt

Methods that estimate heritability and genetic correlations from genome-wide association studies have proven to be powerful tools for investigating the genetic architecture of common diseases and exposing unexpected relationships between disorders. Many relevant studies employ a case-control design, yet most methods are primarily geared towards analyzing quantitative traits. Here we investigate the validity of thr...

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Literature Corpus work: 7b74978b-d5d2-5dfc-9830-ff4caaa84821
DOI: 10.1101/256388

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