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Article

Evaluating and improving heritability models using summary statistics.

Nature genetics - 1 Apr 2020

Speed Doug, Holmes John, Balding David J

Abstract excerpt

There is currently much debate regarding the best model for how heritability varies across the genome. The authors of GCTA recommend the GCTA-LDMS-I model, the authors of LD Score Regression recommend the Baseline LD model, and we have recommended the LDAK model. Here we provide a statistical framework for assessing heritability models using summary statistics from genome-wide association studies. Based on 31...

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Identifiers

PMID: 32203469
DOI: 10.1038/s41588-020-0600-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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