Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimating SNP-Based Heritability and Genetic Correlation in Case-Control Studies Directly and with Summary Statistics.

American journal of human genetics - 5 Jul 2018

Weissbrod Omer, Flint Jonathan, Rosset Saharon

Abstract excerpt

Methods that estimate SNP-based heritability and genetic correlations from genome-wide association studies have proven to be powerful tools for investigating the genetic architecture of common diseases and exposing unexpected relationships between disorders. Many relevant studies employ a case-control design, yet most methods are primarily geared toward analyzing quantitative traits. Here we investigate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Disease
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Genotype

Share to Models, Genetic

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 29979983
DOI: 10.1016/j.ajhg.2018.06.002
PMCID: PMC6035374

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimating SNP-Based Heritability and Genetic Correlation in Case-Control Studies Directly and with Summary Statistics.PMID 29979983Read ↗

Estimating Heritability and Genetic Correlation in Case Control Studies Directly and with Summary StatisticsSemantic proximity Read ↗

Concepts, estimation and interpretation of SNP-based heritability.Semantic proximity Read ↗

Measuring missing heritability: inferring the contribution of common variants.Semantic proximity Read ↗

SNP-based heritability and selection analyses: Improved models and new results.Semantic proximity Read ↗

Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.Semantic proximity Read ↗

Risk in Relatives, Heritability, SNP-Based Heritability, and Genetic Correlations in Psychiatric Disorders: A Review.Semantic proximity Read ↗

A review of SNP heritability estimation methods.Semantic proximity Read ↗

Importance of Diversity in Precision Medicine: Generalizability of Genetic Associations Across Ancestry Groups Toward Better Identification of Disease Susceptibility Variants.Semantic proximity Read ↗

Improving Polygenic Prediction in Ancestrally Diverse PopulationsSemantic proximity Read ↗

Evaluating and improving heritability models using summary statistics.Semantic proximity Read ↗

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data.Semantic proximity Read ↗

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.