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Article

Mapping the heritability of disease: a nationwide study.

Nature communications - 17 Mar 2026

Auning Janne, Trabjerg Betina B, Dreier Julie Werenberg, Vilhjálmsson Bjarni Jóhann, Christensen Jakob

Abstract excerpt

Heritability estimates are essential for understanding genetic and environmental contributions to disease, yet large-scale studies remain scarce. In this study, we leverage the Danish national health registers, including medical records for more than 10 million individuals, to estimate heritability for more than 1000 health outcomes. We estimate heritability using both twins and siblings born in Denmark between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41844607
DOI: 10.1038/s41467-026-69991-z
PMCID: PMC13144670

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