Article
Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS.
Nature genetics - 1 Apr 2021
Peyrot Wouter J, Price Alkes L
Abstract excerpt
Psychiatric disorders are highly genetically correlated, but little research has been conducted on the genetic differences between disorders. We developed a new method (case-case genome-wide association study; CC-GWAS) to test for differences in allele frequency between cases of two disorders using summary statistics from the respective case-control GWAS, transcending current methods that require individual-level...
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