Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS

Abstract excerpt

Psychiatric disorders are highly genetically correlated, and many studies have focused on their shared genetic components. However, little research has been conducted on the genetic differences between psychiatric disorders, because case-case comparisons of allele frequencies among cases currently require individual-level data from cases of both disorders. We developed a new method (CC-GWAS) to test for difference...

Topics

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• Axons
• Bipolar Disorder
• Datasets as Topic
• Depressive Disorder, Major
• Gene Expression
• Genetic Loci
• Kruppel-Like Transcription Factors
• Schizophrenia

Identifiers and source

Literature Corpus work

333bfa04-089f-57f1-9980-92aaba5528fc

DOI

10.1101/2020.03.04.977389