CCAFE: Estimating case and control allele frequencies from GWAS summary statistics.

Abstract excerpt

Genetic summary statistics can be used in a variety of analyses, such as causal inference, genetic correlation, and risk scores, to provide insights into the genetic architecture of conditions and traits. However, complete statistics are often not reported, limiting the utility of these data. Indeed, many post hoc analyses of diseases require case and control allele frequencies (AFs), which are not always...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Case-Control Studies
• Share to Gene Frequency
• Share to Genetic Predisposition to Disease