Article

Epigenomic signatures as circulating and predictive biomarkers in sarcomatoid renal cell carcinoma

2023-11-28

Abstract excerpt

Renal cell carcinoma with sarcomatoid differentiation (sRCC) is associated with poor survival and heightened response to immune checkpoint inhibitors (ICIs). Two major barriers to improving outcomes for sRCC are (1) a limited understanding of its gene regulatory programs and (2) difficulty identifying sarcomatoid differentiation on tumor biopsies due to spatial heterogeneity. To address these challenges, we charac...

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Literature Corpus work: 7b4fb8c6-1d7b-587f-96ad-f27e1ef132a0
DOI: 10.1101/2023.11.27.568827

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