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Article

APOBEC family reshapes the immune microenvironment and therapy sensitivity in clear cell renal cell carcinoma.

Clinical and experimental medicine - 9 Sept 2024

Huang Guiying, Zhan Xianlin, Shen Lihong, Lou Luping, Dai Yuehong, Jiang Aiming, Gao Yuzhen, Wang Yanzhong, Xie Xinyou, Zhang Jun

Abstract excerpt

Emerging evidence suggests that the APOBEC family is implicated in multiple cancers and might be utilized as a new target for cancer detection and treatment. However, the dysregulation and clinical implication of the APOBEC family in clear cell renal cell cancer (ccRCC) remain elusive. TCGA multiomics data facilitated a comprehensive exploration of the APOBEC family across cancers, including ccRCC. Remodeling...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39249558
DOI: 10.1007/s10238-024-01465-2
PMCID: PMC11383847

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