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A single-cell map of dynamic chromatin landscapes of immune cells in renal cell carcinoma

6 Jun 2022

Abstract excerpt

Abstract A complete chart of the chromatin regulatory elements of immune cells in patients with cancer and their dynamic behavior is necessary to understand the developmental fates and guide therapeutic strategies. Here, we map the single-cell chromatin landscape of immune cells from blood, normal tumor-adjacent kidney tissue and malignant tissue from patients with early-stage clear cell renal cell carcinoma...

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PMID: 35668194
DOI: 10.1038/s43018-022-00391-0

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