Article

Antibacterial Activity of the p53 Tumor Suppressor Protein - How Strong Is the Evidence?

2025-04-03

Abstract excerpt

p53 tumor suppressor is best known from controlling cell cycle, apoptosis, DNA repair, and metabolism, but it also regulates immunity and is able to impede the live cycle of viruses. For this reason these infectious agents encode proteins, which inactivate p53. However, what is less known is that p53 can also be inactivated by human pathogenic bacteria. It is probably not a collateral damage, but specific targetin...

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Literature Corpus work: 7a2e24ec-e19c-55c1-993a-591813cb928d
DOI: 10.20944/preprints202504.0259.v1

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