Article
Blinded by the Light: The Growing Complexity of p53.
Cell - 1 May 2009
Vousden Karen H, Prives Carol
Abstract excerpt
While the tumor suppressor functions of p53 have long been recognized, the contribution of p53 to numerous other aspects of disease and normal life is only now being appreciated. This burgeoning range of responses to p53 is reflected by an increasing variety of mechanisms through which p53 can function, although the ability to activate transcription remains key to p53's modus operandi. Control of p53's...
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