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Article

Interactions between the tumor suppressor p53 and immune responses.

Current opinion in oncology - 1 Jan 2013

Menendez Daniel, Shatz Maria, Resnick Michael A

Abstract excerpt

PURPOSE OF REVIEW: The p53 tumor suppressor is a master regulator of antitumor defenses through its control of growth arrest, senescence and apoptosis. In recent years, p53 regulation was found to extend to a variety of biological processes including autophagy, fertility, metabolism and immune responses. Here, we focus on the role of p53 in the immune system. We explore the relationship between p53 and the innate...

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Identifiers

PMID: 23150340
DOI: 10.1097/CCO.0b013e32835b6386

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