Article

Correlating p53 immunostaining patterns with somatic TP53 mutation and functional properties of mutant p53 in triple-negative breast cancer

2024-07-19

Abstract excerpt

<title>Abstract</title> <p>Immunohistochemical (IHC) staining pattern of p53 has been recognized as a potential surrogate marker for TP53 mutations across diverse cancer types. Nevertheless, interpretative criteria for p53 IHC expression as a predictive tool for TP53 mutation in triple-negative breast cancer (TNBC) have not been established yet. A total of 113 TNBC cases were analyzed for p53 IHC pattern and soma...

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Literature Corpus work: 7977944b-1ff2-507b-ab65-d6ea65ebdb09
DOI: 10.21203/rs.3.rs-4645054/v1

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