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Article

p53 protein expression patterns associated with TP53 mutations in breast carcinoma.

Breast cancer research and treatment - 1 Aug 2024

Anderson Sarah A, Bartow Brooke B, Harada Shuko, Siegal Gene P, Wei Shi, Dal Zotto Valeria L, Huang Xiao

Abstract excerpt

PURPOSE: The importance of a TP53 mutation has been demonstrated in several tumor types, including breast cancer (BC). However, the accuracy of p53 protein expression as a predictor of gene mutation has not been well studied in BC. Therefore, we evaluated p53 protein expression associated with TP53 mutations in breast cancers from 64 patients. METHODS: TP53 mutation was examined using next-generation sequencing...

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Identifiers

PMID: 38900212
DOI: 10.1007/s10549-024-07357-z
PMCID: PMC11230957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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