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Article

Immunohistochemical correlates of TP53 somatic mutations in cancer.

Oncotarget - 4 Oct 2016

Murnyák Balázs, Hortobágyi Tibor

Abstract excerpt

Despite controversy on the correlation between p53 accumulation and TP53 mutational status, immunohistochemical (IHC) detection of overexpressed protein has long been used as a surrogate method for mutation analysis. The aim of our study was to characterise the IHC expression features of TP53 somatic mutations and define their occurrence in human cancers. A large-scale database analysis was conducted in the IARC...

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Identifiers

PMID: 27626311
DOI: 10.18632/oncotarget.11912
PMCID: PMC5323125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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