Article

metaAPA: a tool for integration of PolyA site predictions from single-cell and spatial transcriptomics

2025-10-01

Abstract excerpt

<h4>Motivation</h4> Single-cell 3’-tagging sequencing, such as that provided by 10x Genomics, can be utilized to study alternative polyadenylation (APA). APA can affect RNA function, stability, and subcellular localization, thereby influencing development and disease processes. Currently, computational tools based on various algorithms, such as Sierra, polyApipe, and SCAPE, have been developed to infer polyA site...

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Literature Corpus work: 00e2ea80-abcd-5d2f-a4a9-f61ae789d887
DOI: 10.1101/2025.09.29.679268

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