Article

Single-molecule variation in telomeric sequence and structure across humans

2026-05-05

Abstract excerpt

The repetitive architectures of telomeric and subtelomeric regions have obscured studies of their genetic variation and chromatin organization across the human population. Here, we integrate near-complete diploid genome assemblies from 212 individuals with matched long-read sequencing data to construct an atlas of 316,146 telomere-spanning molecules across 12,080 chromosome-end-resolved telomere arrays. This atlas...

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Literature Corpus work: 7900ea61-dc1e-5120-8161-4f9329f56cf9
DOI: 10.64898/2026.05.01.722200

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