Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of telomere variant repeats using long reads enables allele-specific telomere length estimation.

BMC bioinformatics - 17 May 2024

Stephens Zachary, Kocher Jean-Pierre

Abstract excerpt

Telomeres are regions of repetitive DNA at the ends of linear chromosomes which protect chromosome ends from degradation. Telomere lengths have been extensively studied in the context of aging and disease, though most studies use average telomere lengths which are of limited utility. We present a method for identifying all 92 telomere alleles from long read sequencing data. Individual telomeres are identified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosomal and Genetic Variations
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitochondrial Function and Pathology

Share to Repetitive Sequences, Nucleic Acid

Share to Sequence Analysis, DNA

Share to Telomere

Share to Telomeres, Telomerase, and Senescence

Source

Open in PubMed Open full text

Identifiers

PMID: 38755561
DOI: 10.1186/s12859-024-05807-5
PMCID: PMC11100205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of telomere variant repeats using long reads enables allele-specific telomere length estimation.PMID 38755561Read ↗

Characterization of telomere variant repeats using long reads enables allele-specific telomere length estimationSemantic proximity Read ↗

Telomere variant sequences encode the genetic blueprint for allele-specific telomere lengthSemantic proximity Read ↗

High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancerSemantic proximity Read ↗

High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer.Semantic proximity Read ↗

Telogator: a method for reporting chromosome-specific telomere lengths from long readsSemantic proximity Read ↗

High-throughput telomere length measurement at nucleotide resolution using the PacBio high fidelity sequencing platformSemantic proximity Read ↗

Single-molecule variation in telomeric sequence and structure across humansSemantic proximity Read ↗

Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes.Semantic proximity Read ↗

Computel: Computation of Mean Telomere Length from Whole-Genome Next-Generation Sequencing DataSemantic proximity Read ↗

Nanopore whole-genome sequencing reveals conserved chromosome-specific telomere architecture across tissues and populationsSemantic proximity Read ↗

Multidimensional telomere diversity and inheritance at individual and population scalesSemantic proximity Read ↗

Haplotype Diversity and Sequence Heterogeneity of Human TelomeresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.