Article

Multidimensional telomere diversity and inheritance at individual and population scales

2026-08-24

Abstract excerpt

Variation in telomere length, sequence composition and epigenetic state influences genome stability, aging and disease, yet its high-resolution characterization across species remains challenging. Here we present TeloXplorer, a computational framework for long-read data that jointly profiles telomere length, telomere variant repeats (TVRs) and DNA methylation at chromosome-end and haplotype resolution. Across simu...

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Literature Corpus work: 638d8b98-3882-59cf-916f-d731654da589
DOI: 10.64898/2026.08.19.745664

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