Article

Nanopore whole-genome sequencing reveals conserved chromosome-specific telomere architecture across tissues and populations

2025-12-12

Abstract excerpt

Telomeres are repetitive nucleoprotein structures that cap the ends of linear chromosomes and are essential for maintaining genomic stability. While individual chromosome ends maintain distinct telomere lengths, the extent of this conservation across tissues and populations remains unclear due to the difficulty of analyzing repetitive telomeric sequences. Here, we show that high-coverage whole-genome Nanopore sequ...

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Literature Corpus work: 4d40cffa-5585-540c-97dd-256fa0efb1c0
DOI: 10.64898/2025.12.10.693405

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