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Article

High-throughput single-molecule mapping links subtelomeric variants and long-range haplotypes with specific telomeres.

Nucleic acids research - 19 May 2017

Young Eleanor, Pastor Steven, Rajagopalan Ramakrishnan, McCaffrey Jennifer, Sibert Justin, Mak Angel C Y, Kwok Pui-Yan, Riethman Harold, Xiao Ming

Abstract excerpt

Accurate maps and DNA sequences for human subtelomere regions, along with detailed knowledge of subtelomere variation and long-range telomere-terminal haplotypes in individuals, are critical for understanding telomere function and its roles in human biology. Here, we use a highly automated whole genome mapping technology in nano-channel arrays to analyze large terminal human chromosome segments extending from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28180280
DOI: 10.1093/nar/gkx017
PMCID: PMC5605236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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