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Single-cell microfluidics enabled dynamic evaluation of drug combinations on antibiotic resistance bacteria

16 Jun 2023

Abstract excerpt

The rapid spread of antibiotic resistance has become a significant threat to global health, yet the development of new antibiotics is outpaced by emerging new resistance. To treat multidrug-resistant bacteria and prolong the lifetime of existing antibiotics, a productive strategy is to use combinations of antibiotics and/or adjuvants. However, evaluating drug combinations is primarily based on end-point...

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PMID: 37343360
DOI: 10.1016/j.talanta.2023.124814

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