Article

Bacterial droplet-based single-cell RNA-seq reveals heterogeneity in bacterial populations and in response to antibiotic perturbation

2022-08-02

Abstract excerpt

We introduce BacDrop, a highly scalable technology for bacterial single-cell RNA sequencing that has overcome many challenges hindering the development of scRNA-seq in bacteria. BacDrop can be applied to thousands or millions of cells from both gram-negative and gram-positive species. It features universal ribosomal RNA depletion and combinatorial barcodes that enable multiplexing and massively parallel sequencing...

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Literature Corpus work: 6f9a7ba3-e5af-5012-8cf8-ff1061f10c1a
DOI: 10.1101/2022.08.01.502326

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