Article

Transfer learning enables prediction of <i>CYP2D6</i> haplotype function

2019-06-27

Abstract excerpt

Cytochrome P450 2D6 ( CYP2D6 ) is a highly polymorphic gene whose protein product metabolizes more than 20% of clinically used drugs. Genetic variations in CYP2D6 are responsible for interindividual heterogeneity in drug response that can lead to drug toxicity and ineffective treatment, making CYP2D6 one of the most important pharmacogenes. Prediction of CYP2D6 phenotype relies on curation of literature-derived...

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Literature Corpus work: 78518e97-50a6-5874-af16-534bef05c3cb
DOI: 10.1101/684357

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