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Article

Cypiripi: exact genotyping of CYP2D6 using high-throughput sequencing data.

Bioinformatics (Oxford, England) - 15 Jun 2015

Numanagić Ibrahim, Malikić Salem, Pratt Victoria M, Skaar Todd C, Flockhart David A, Sahinalp S Cenk

Abstract excerpt

MOTIVATION: CYP2D6 is highly polymorphic gene which encodes the (CYP2D6) enzyme, involved in the metabolism of 20-25% of all clinically prescribed drugs and other xenobiotics in the human body. CYP2D6 genotyping is recommended prior to treatment decisions involving one or more of the numerous drugs sensitive to CYP2D6 allelic composition. In this context, high-throughput sequencing (HTS) technologies provide a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 26072492
DOI: 10.1093/bioinformatics/btv232
PMCID: PMC4542776

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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