Article

Runx/Cbfβ regulates the development of tolerogenic Thetis cells

2025-08-31

Abstract excerpt

Establishing immune tolerance to gut microbiota and food antigens upon first exposures during early life is essential to prevent inflammatory bowel diseases and food allergy and depends on induction of peripherally induced Rorγt expressing regulatory T (Rorγt + pTreg) cells 1, 2, 3, 4, 5, 6 . Recent studies have identified a critical role for Rorγt expressing antigen-presenting cells (APC), Thetis cells (TCs), i...

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Literature Corpus work: 78352d0a-c540-5eab-a047-0a62cbbd6dd8
DOI: 10.1101/2025.08.27.672523

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