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Microbiota-instructed regulatory T cell differentiation is mediated by a distinct ROR <i>γ</i> t <sup>+</sup> antigen presenting cell subset

2021-11-20

Abstract excerpt

The mutualistic relationship of gut-resident microbiota and cells of the host immune system promotes homeostasis that ensures maintenance of the microbial community and of a poised, but largely non-aggressive, immune cell compartment 1, 2 . Consequences of disturbing this balance, by environmental or genetic factors, include proximal inflammatory conditions, like Crohn’s disease, and systemic illnesses, both meta...

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Identifiers and source

Literature Corpus work
19a287ed-94e0-5b01-8f47-ad7799cb4b07
DOI
10.1101/2021.11.19.469318
Open publication

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