Article

Prdm16-dependent antigen-presenting cells induce tolerance to intestinal antigens

2024-07-24

Abstract excerpt

The gastrointestinal tract is continuously exposed to foreign antigens in food and commensal microbes with potential to induce adaptive immune responses. Peripherally induced T regulatory (pTreg) cells are essential for mitigating inflammatory responses to these agents 1–4 . While RORγt + antigen-presenting cells (RORγt-APCs) were shown to program gut microbiota-specific pTreg 5–7 , their definition remains inc...

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Literature Corpus work: 6b7f0de7-0dcb-5e88-b0e8-c749b325fe34
DOI: 10.1101/2024.07.23.604803

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