Article

Thetis cells induce food-specific Treg cell differentiation and oral tolerance

2024-05-10

Abstract excerpt

The intestinal immune system must establish tolerance to food antigens to prevent onset of allergic and inflammatory diseases. Peripherally generated regulatory T (pTreg) cells play an essential role in suppressing inflammatory responses to allergens; however, the antigen-presenting cell (APC) that instructs food-specific pTreg cells is not known. Here, we show that antigen presentation and TGF-β activation by a s...

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Literature Corpus work: a6142e68-43fa-5e2f-b25a-b94d3c87c933
DOI: 10.1101/2024.05.08.592952

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