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Innate Lymphoid Cells: Emerging Insights in Development, Lineage Relationships, and Function

26 Mar 2012

Abstract excerpt

Innate lymphoid cells (ILCs) are immune cells that lack a specific antigen receptor yet can produce an array of effector cytokines that in variety match that of T helper cell subsets. ILCs function in lymphoid organogenesis, tissue remodeling, antimicrobial immunity, and inflammation, particularly at barrier surfaces. Their ability to promptly respond to insults inflicted by stress-causing microbes strongly...

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PMID: 22224763
DOI: 10.1146/annurev-immunol-020711-075053

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