Article

Interplay between charge distribution and DNA in shaping HP1 paralog phase separation and localization

2023-05-30

Abstract excerpt

<h4> Abstract </h4> The heterochromatin protein 1 (HP1) family is a crucial component of heterochromatin with diverse functions in gene regulation, cell cycle control, and cell differentiation. In humans, there are three paralogs, HP1α, HP1β, and HP1γ, which exhibit remarkable similarities in their domain architecture and sequence properties. Nevertheless, these paralogs display distinct behaviors in liquid-liqu...

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Literature Corpus work: 78038534-5a16-50d5-a560-4cb183ea2a43
DOI: 10.1101/2023.05.28.542535

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