Article

Heterochromatin organization and liquid-liquid phase separation: it is not about “if” but about “when”

2026-06-07

Abstract excerpt

Heterochromatin is a membraneless compartment within the cell nucleus. In recent years, a controversy arose on whether heterochromatin organization is driven by liquid-liquid phase separation or not. While many heterochromatin proteins were shown to undergo liquid-liquid phase separation in vitro , other studies reported that this does not happen in cells. Here, we tested the ability of heterochromatin proteins t...

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Literature Corpus work: 562cfd68-c725-5c83-b7a6-aa57b2faf683
DOI: 10.64898/2026.06.03.729812

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