Article

Is there a role of phase partitioning in coordinating DNA damage response?

2020-08-27

Abstract excerpt

DNA repair pathways are critical processes that need both spatial and temporal fine regulation. Liquid-liquid phase separation (LLPS) is a way to concentrate biochemical reactions, while excluding non-interacting components. Protein’s disordered domains, as well as RNA, favor condensation to modulate this process. Recent insights about phase-separation mechanisms pointed to new fascinating models that could explai...

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Literature Corpus work: 5cf53660-4d79-547d-b1b7-44d8de4f9f67
DOI: 10.1101/2020.08.26.268763

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